Probiotic-Based Sanitation in the Built Environment—An Alternative to Chemical Disinfectants

The use of conventional chemical disinfectants is a common practice in built environments and has drastically increased response to the COVID-19 pandemic. While effective for instantaneous disinfection, application indoor surfaces associated with recontamination prone select antimicrobial-resistant pathogens. In contrast, probiotic-based sanitation (PBS) relies on premise that probiotic bacteria, namely apathogenic Bacillus spp., when combined eco-friendly detergents applied can outcompete exclude Recent situ studies assessing PBS healthcare settings have demonstrated overwhelmingly positive results, including significant reductions pathogen burden, genes nosocomial infections, yet these are limited duration scope. Here, we review results Bacillus-based practice, identify knowledge gaps discuss considerations widespread environments. time cleaning disinfection come forefront, may offer an attractive, sustainable alternative disinfectants.